Simplifying Drupal's Admin Experience (AX)

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Drupal has long been known for having a steeper learning curve than other CMS options. What are the things that we, as site builders and developers, can do to make life easier for the editors who spend their time keeping Drupal sites up to date? I'll share some ideas I like to use, but it would be ideal if this could be more of a BOF-style open discussion. Also feel free to share any points you've experienced as a Drupal editor.